ea0041ep256 | Clinical case reports - Pituitary/Adrenal | ECE2016
Lazar Elena
, Ilie Mirela
, Tanasescu Radu
, Popescu Bogdan
, Badiu Corin
Background: X-linked adrenoleukodystrophy (ALD) is a peroxisomal disorder of beta-oxidation that results in accumulation of very long chain fatty acids (VLCFAs) in various tissues. The clinical phenotype of X-ALD in adults is variable and involves adrenal, gonadal and nervous system dysfunction (adrenomyeloneuropathy, AMN). Patients with AMN typically develop spastic paraparesis due to progressive degeneration of the cerebral white matter.Objective: To r...